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Randy Lewis

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Biology

Professor - Biology Department

Professor

Contact Information

DialPhone: 435-797-9291
SendEmail: randy.lewis@usu.edu


Educational Background

PhD, Biochemistry, University of California San Diego, 1978
Bifunctional Crosslinking Reagents
MS, Biochemistry, University of California San Diego, 1974
BS, Chemistry, (Biochemistry), California Institute of Technology, 1972

Awards

USU College of Science Undergraduate Research Mentor of the Year, 2016

College of Science

Publications - Abstracts

    Publications - Books & Book Chapters

      * Has not been peer reviewed

      Publications - Fact Sheets

        * Has not been peer reviewed

        Publications - Curriculum

          * Has not been peer reviewed

          Publications - Journal Articles

            Academic Journal

          • Teulé, F., Addison, B., Cooper, A.R, Ayon, J., Henning, R.W, Benmore, C.J, Holland, G.P, Yarger, J.L, Lewis, R., Combining flagelliform and dragline spider silk motifs to produce tunable synthetic biopolymer fibers. Biopolymers, 97(6) , 419-431.
          • Hudspeth, M., Nie, ., Chen , W., Lewis, R., Effect of Loading Rate on Mechanical Properties and Fracture Morphology of Spider Silk. Biomacromolecules, , 13 (8), , 2240–2246.
          • Melinda, C., Thomas, ., Amanda , .E, , Lewis, R., Elucidating Metabolic Pathways for Amino Acid Incorporation Into Dragline Spider Silk using 13C Enrichment and Solid State NMR. Comparative Biochemistry and Physiology, Part A, 159(3) , 219-224.
          • An, B., Hinman, M.B, Holland, G.P, Yarger, J.L, Lewis, R., Inducing β-Sheets Formation in Synthetic Spider Silk Fibers by Aqueous Post-Spin Stretching. Biomacromolecules, 12 (6), , 2375–2381.
          • Kyle, L., John, T., Schatzl, H., Lewis, R., Introducing a rigid loop structure from deer into mouse prion protein increases its propensity for misfolding in vitro. Plos One, 8:6, e66715.
          • Menezes, G., Teule, F., Lewis, R., Silva, L., Rech, E., Nanoscale investigations of synthetic spider silk fibers modified by physical and chemical processes. Polymer Journal, 45, 997-1006.
          • Adrianos, S., Teule, F., Hinman, M., Jones, J., Weber, W., Yarger, J., Lewis, R., , Nephila clavipes Flagelliform Silk-like GGX Motifs Contribute to Extensibility and Spacer Motifs Contribute to Strength in Synthetic Spider Silk Fibers. Biomacromolecules, 14, 1751-1760.
          • An, B., Jenkins, J.E, Sampath, S., Holland, G.P, Hinman, M., Yarger, .L, Lewis, R., Reproducing Natural Spider Silks’ Co-Polymer Behavior in Synthetic Silk Mimics. Biomacromolecules, 13:12, 3938-3948.
          • Teulé, F., Miao, Y., Sohn, B., Kim, Y., Hull, J., Fraser, M. , Lewis, R., Jarvis, D.L, Silkworms Transformed with ChimericSilkworm/ Spider Silk Genes Spin Composite Silk Fibers with Improved Mechanical Properties. PNAS , 109 (3) , 923-928.
          • Steinkraus, H.B, Rothfuss, H., Jones, J.A, Dissen, E., Shefferly, E., Lewis, R., The absence of detectable fetal microchimerism in nontransgenic goats (Capra aegagrus hircus) bearing transgenic offspring. J. of Animal Science , 90(2): , 481-488.
          • Jones, J., Lewis, R., (2016). Secondary Structure Adopted by the Gly-Gly-X Repetitive Regions of Dragline Spider Silk. , doi: 10.3390/ijms17122023
          • Jones, J., Harris, T.I, Oliveira, P.F, Bell, B.E, Alhabib, A., Lewis, R., Importance of Heat and Pressure for Solubilization of Recombinant Spider Silk Proteins in Aqueous Solution.. International Journal of Molecular Sciences17
          • Copeland, C.G, Bell, B. , Christensen, C.D, Lewis, R.V, (2015). Development of a Process for the Spinning of Synthetic Spider Silk . ACS Biomaterials Science and Engineering , 1:7, 577–584 . doi: DOI: 10.1021/acsbiomaterials.5b00092
          • Jones, J.A, Harris, T.I, Tucker, C. , Berg, K. , Christy, S.Y, Day, B. , Gaztambide, D.A, Needham, N. , Ruben, A.L, Oliveira, P.F, Decker, R.E, Lewis, R.V, (2015). More Than Just Fibers: An Aqueous Method for the Production of Innovative Recombinant Spider Silk Protein Materials. Biomacromolecules , 16 :(4), pp 1418–1425. doi: DOI: 10.1021/acs.biomac.5b00226)
          • An, B., Tang-Schomer, M.D, Huang, W., He, J., Jones, J.A, Lewis, R., Kaplan, D.L, (2015). Physical and biological regulation of neuron regenerative growth and network formation on recombinant dragline silks.. Biomaterials, 48, 137-46.
          • Zhu, B., Li , W., Lewis, R., Segre, C.U, Wang, R., (2015). E-spun composite fibers of collagen and dragline silk protein: fiber mechanics, biocompatibility, and application in stem cell differentiation.. Biomacromolecules, 16:1, 202-13.
          • Lewis, R., (2014). E‑Spun Composite Fibers of Collagen and Dragline Silk Protein Cell Differentiation: FiberMechanics, Biocompatibility, and Application in Stem. Biomacromolecules, 16, 202-213. doi: doi: 10.1021/bm501403f
          • Tucker, C.L, Jones, J.A, Bringhurst, H.N, Copeland, C.G, Addison, J.B, Weber, W.S, Mou, Q., Yarger, J.L, Lewis, R., (2014). Mechanical and physical properties of recombinant spider silk films using organic and aqueous solvents.. Biomacromolecules, 15:8, 3158-70.
          • Xing, C., Munro, T., Jensen, C., White, B., Ban, H., Copeland, C., Lewis, R., (2014). Thermophysical property measurement of electrically nonconductive fibers by the electrothermal technique. Measurement. Science. Technology, 25, doi: doi:10.1088/0957-0233/25/11/115604
          • Xing, C., Munro, T., White, B., Ban, H., Copeland, C., Lewis, R., (2014). Thermophysical properties of the dragline silk of Nephila clavipes spider. Polymer, 55, 4226-4234.
          • Albertson, A., TEule, F., Weber, W., Yarger, J., Lewis, R., (2014). Effects of different post-spin stretching conditions on the mechanical properties of synthetic spider silk fibers, . Journal of the Mechanical Behavior of Biomedical Materials , 29, 225-234.
          • Albertson, A.E, Teulé, F., Weber, W., Yarger, J.L, Lewis, R., (2014). Effects of different post-spin stretching conditions on the mechanical properties of synthetic spider silk fibers.. Journal of the mechanical behavior of biomedical materials, 29, 225-34.
          • Adrianos, S.L, Teulé, F., Hinman, M.B, Jones, J.A, Weber, W.S, Yarger, J.L, Lewis, R., (2013). Nephila clavipes Flagelliform silk-like GGX motifs contribute to extensibility and spacer motifs contribute to strength in synthetic spider silk fibers.. Biomacromolecules, 14:6, 1751-60.
          • Steinkraus, H.B, Rothfuss, H., Jones, J.A, Dissen, E., Shefferly, E., Lewis, R., (2012). The absence of detectable fetal microchimerism in nontransgenic goats (Capra aegagrus hircus) bearing transgenic offspring.. Journal of animal science, 90:2, 481-8.
          • Teulé, F., Miao, Y.G, Sohn, B.H, Kim, Y.S, Hull, J.J, Fraser, Jr, M.J, Lewis, R., Jarvis, D.L, (2012). Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties.. Proceedings of the National Academy of Sciences of the United States of America, 109:3, 923-8.
          • Perry, D.J, Bittencourt, D., Siltberg-Liberles, J., Rech, E.L, Lewis, R., (2010). Piriform spider silk sequences reveal unique repetitive elements.. Biomacromolecules, 11:11, 3000-6.
          • Jenkins, J.E, Creager, M.S, Butler, E.B, Lewis, R., Yarger, J.L, Holland, G.P, (2010). Solid-state NMR evidence for elastin-like beta-turn structure in spider dragline silk.. Chemical communications (Cambridge, England), 46:36, 6714-6.
          • Creager, M.S, Jenkins, J.E, Thagard-Yeaman, L.A, Brooks, A.E, Jones, J.A, Lewis, R., Holland, G.P, Yarger, J.L, (2010). Solid-state NMR comparison of various spiders' dragline silk fiber.. Biomacromolecules, 11:8, 2039-43.
          • Bittencourt, D., Dittmar, K., Lewis, R., Rech, E.L, (2010). A MaSp2-like gene found in the Amazon mygalomorph spider Avicularia juruensis.. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 155:4, 419-26.
          • Jenkins, J.E, Creager, M.S, Lewis, R., Holland, G.P, Yarger, J.L, (2010). Quantitative Correlation between the protein primary sequences and secondary structures in spider dragline silks.. Biomacromolecules, 11:1, 192-200.
          • Choresh, O., Bayarmagnai, B., Lewis, R., (2009). Spider web glue: two proteins expressed from opposite strands of the same DNA sequence.. Biomacromolecules, 10:10, 2852-6.
          • Teulé, F., Cooper, A.R, Furin, W.A, Bittencourt, D., Rech, E.L, Brooks, A., Lewis, R., (2009). A protocol for the production of recombinant spider silk-like proteins for artificial fiber spinning.. Nature protocols, 4:3, 341-55.
          • Brooks, A.E, Brooks, B.D, Creager, M.S, Lewis, R., (2009). Analyzing the clustering effects of major ampullate silk mechanical properties - biomed 2009.. Biomedical sciences instrumentation, 45, 232-7.
          • Brooks, B., Brooks, A., Wulff, S.S, Lewis, R., (2009). Identification of problems developing an ultrasensitive immunoassay for the ante mortem detection of the infectious isoform of the CWD-associated prion protein.. Journal of immunoassay & immunochemistry, 30:2, 135-49.
          • Holland, G.P, Jenkins, J.E, Creager, M.S, Lewis, R., Yarger, J.L, (2008). Quantifying the fraction of glycine and alanine in beta-sheet and helical conformations in spider dragline silk using solid-state NMR.. Chemical communications (Cambridge, England)43, 5568-70.
          • Brooks, B.D, Albertson, A.E, Jones, J.A, Speare, J.O, Lewis, R., (2008). Efficient screening of high-signal and low-background antibody pairs in the bio-bar code assay using prion protein as the target.. Analytical biochemistry, 382:1, 60-2.
          • Brooks, A.E, Nelson, S.R, Jones, J.A, Koenig, C., Hinman, M., Stricker, S., Lewis, R., (2008). Distinct contributions of model MaSp1 and MaSp2 like peptides to the mechanical properties of synthetic major ampullate silk fibers as revealed in silico.. Nanotechnology, science and applications, 1, 9-16.
          • Holland, G.P, Creager, M.S, Jenkins, J.E, Lewis, R., Yarger, J.L, (2008). Determining secondary structure in spider dragline silk by carbon-carbon correlation solid-state NMR spectroscopy.. Journal of the American Chemical Society, 130:30, 9871-7.
          • Brooks, A.E, Stricker, S.M, Joshi, S.B, Kamerzell, T.J, Middaugh, C.R, Lewis, R., (2008). Properties of synthetic spider silk fibers based on Argiope aurantia MaSp2.. Biomacromolecules, 9:6, 1506-10.
          • Holland, G.P, Jenkins, J.E, Creager, M.S, Lewis, R., Yarger, J.L, (2008). Solid-state NMR investigation of major and minor ampullate spider silk in the native and hydrated states.. Biomacromolecules, 9:2, 651-7.
          • Garb, J.E, DiMauro, T., Lewis, R., Hayashi, C.Y, (2007). Expansion and intragenic homogenization of spider silk genes since the Triassic: evidence from Mygalomorphae (tarantulas and their kin) spidroins.. Molecular biology and evolution, 24:11, 2454-64.
          • Brooks, A.E, Brothers, T.J, Creager, M.S, Lewis, R., (2007). A novel methodology to explore the viscoelasticity of spider major ampullate silk.. Journal of applied biomaterials & biomechanics : JABB, 5:3, 158-65.
          • Bittencourt, D., Souto, B.M, Verza, N.C, Vinecky, F., Dittmar, K., Silva, Jr, P.I, Andrade, A.C, da Silva, F.R, Lewis, R., Rech, E.L, (2007). Spidroins from the Brazilian spider Nephilengys cruentata (Araneae: Nephilidae).. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 147:4, 597-606.
          • Sorensen, C.M, Rempel, L.A, Nelson, S.R, Francis, B.R, Perry, D.J, Lewis, R., Haas, A.L, Hansen, T.R, (2007). The hinge region between two ubiquitin-like domains destabilizes recombinant ISG15 in solution.. Biochemistry, 46:3, 772-80.
          • Lewis, R., (2006). Spider silk: ancient ideas for new biomaterials.. Chemical reviews, 106:9, 3762-74.
          • Brooks, A.E, Steinkraus, H.B, Nelson, S.R, Lewis, R., (2005). An investigation of the divergence of major ampullate silk fibers from Nephila clavipes and Argiope aurantia.. Biomacromolecules, 6:6, 3095-9.
          • Motriuk-Smith, D., Smith, A., Hayashi, C.Y, Lewis, R., (2005). Analysis of the conserved N-terminal domains in major ampullate spider silk proteins.. Biomacromolecules, 6:6, 3152-9.
          • Tian, M., Lewis, R., (2005). Molecular characterization and evolutionary study of spider tubuliform (eggcase) silk protein.. Biochemistry, 44:22, 8006-12.
          • Brooks, A.E, Creager, M.S, Lewis, R., (2005). Altering the mechanics of spider silk through methanol post-spin drawing.. Biomedical sciences instrumentation, 41, 1-6.
          • Hayashi, C.Y, Blackledge, T.A, Lewis, R., (2004). Molecular and mechanical characterization of aciniform silk: uniformity of iterated sequence modules in a novel member of the spider silk fibroin gene family.. Molecular biology and evolution, 21:10, 1950-9.
          • Holland, G.P, Lewis, R., Yarger, J.L, (2004). WISE NMR characterization of nanoscale heterogeneity and mobility in supercontracted Nephila clavipes spider dragline silk.. Journal of the American Chemical Society, 126:18, 5867-72.
          • Motriuk-Smith, D., Lewis, R., (2004). Brown widow (Latrodectus geometricus) major ampullate silk protein and its material properties.. Biomedical sciences instrumentation, 40, 64-9.
          • Brooks, A.E, Lewis, R., (2004). Probing the elastic nature of spider silk in pursuit of the next designer fiber.. Biomedical sciences instrumentation, 40, 232-7.
          • Watson, R.M, Woody, R.W, Lewis, R., Bohle, D.S, Andreotti, A.H, Ray, B., Miller, K.W, (2001). Conformational changes in pediocin AcH upon vesicle binding and approximation of the membrane-bound structure in detergent micelles.. Biochemistry, 40:46, 14037-46.
          • Hayashi, C.Y, Lewis, R., (2001). Spider flagelliform silk: lessons in protein design, gene structure, and molecular evolution.. BioEssays : news and reviews in molecular, cellular and developmental biology, 23:8, 750-6.
          • Hinman, M.B, Jones, J.A, Lewis, R., (2000). Synthetic spider silk: a modular fiber.. Trends in biotechnology, 18:9, 374-9.
          • Hayashi, C.Y, Lewis, R., (2000). Molecular architecture and evolution of a modular spider silk protein gene.. Science (New York, N.Y.), 287:5457, 1477-9.
          • Hayashi, C.Y, Shipley, N.H, Lewis, R., (1999). Hypotheses that correlate the sequence, structure, and mechanical properties of spider silk proteins.. International journal of biological macromolecules, 24:2-3, 271-5.
          • Colgin, M.A, Lewis, R., (1998). Spider minor ampullate silk proteins contain new repetitive sequences and highly conserved non-silk-like "spacer regions".. Protein science : a publication of the Protein Society, 7:3, 667-72.
          • Hayashi, C.Y, Lewis, R., (1998). Evidence from flagelliform silk cDNA for the structural basis of elasticity and modular nature of spider silks.. Journal of molecular biology, 275:5, 773-84.
          • Parkhe, A.D, Seeley, S.K, Gardner, K., Thompson, L., Lewis, R., (1997). Structural studies of spider silk proteins in the fiber.. Journal of molecular recognition : JMR, 10:1, 1-6.
          • Lewis, R., Hinman, M., Kothakota, S., Fournier, M.J, (1996). Expression and purification of a spider silk protein: a new strategy for producing repetitive proteins.. Protein expression and purification, 7:4, 400-6.
          • Kadokami, Y., Lewis, R., (1995). Reverse electrophoresis to concentrate DNA fractions.. Analytical biochemistry, 226:1, 193-5.
          • Kadokami, Y., Ruess, S.L, Mills, B.W, Lewis, R., (1995). Cycle DNA sequencing from a gel band.. BioTechniques, 18:2, 226.
          • Kadokami, Y., Deike, C.A, Lewis, R., (1995). Precipitation of the template DNA can be omitted after NaOH denaturation in double-stranded DNA sequencing.. BioTechniques, 18:1, 40-1.
          • Kadokami, Y., Lewis, R., (1994). Repeated PCR of a gel band can be used to obtain a single PCR band.. BioTechniques, 17:3, 438.
          • Kadokami, Y., Colgin, M.A, Yesgar, P.W, Lewis, R., (1994). ScreenMax plasmid mini-prep: super rapid plasmid DNA extraction method.. BioTechniques, 17:3, 580-4.
          • Hiddinga, H.J, Isaak, D.D, Lewis, R., (1994). Enkephalin-containing peptides processed from proenkephalin significantly enhance the antibody-forming cell responses to antigens.. Journal of immunology (Baltimore, Md. : 1950), 152:8, 3748-59.
          • Hinman, M.B, Lewis, R., (1992). Isolation of a clone encoding a second dragline silk fibroin. Nephila clavipes dragline silk is a two-protein fiber.. The Journal of biological chemistry, 267:27, 19320-4.
          • Paik, S.R, Lewis, R., (1992). Purification and characterization of a putative proenkephalin cleaving enzyme.. Archives of biochemistry and biophysics, 296:2, 617-29.
          • Steadman, B.L, Thompson, K.C, Middaugh, C.R, Matsuno, K., Vrona, S., Lawson, E.Q, Lewis, R., (1992). The effects of surface adsorption on the thermal stability of proteins.. Biotechnology and bioengineering, 40:1, 8-15.
          • Mach, H., Middaugh, C.R, Lewis, R., (1992). Detection of proteins and phenol in DNA samples with second-derivative absorption spectroscopy.. Analytical biochemistry, 200:1, 20-6.
          • Kraemer, W.J, Lewis, R., Triplett, N.T, Koziris, L.P, Heyman, S., Noble, B.J, (1992). Effects of hypnosis on plasma proenkephalin peptide F and perceptual and cardiovascular responses during submaximal exercise.. European journal of applied physiology and occupational physiology, 65:6, 573-8.
          • Kadokami, Y., Lewis, R., (1992). Instant vacublotting of DNA and RNA.. BioTechniques, 12:1, 79-80.
          • Hinman, M., Dong, Z., Xu, M., Lewis, R., (1992). Spider silk: a mystery starting to unravel.. Results and problems in cell differentiation, 19, 227-54.
          • Mach, H., Middaugh, C.R, Lewis, R., (1992). Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins.. Analytical biochemistry, 200:1, 74-80.
          • Matsuno, K., Lewis, R., Middaugh, C.R, (1991). The interaction of gamma-crystallins with model surfaces.. Archives of biochemistry and biophysics, 291:2, 349-55.
          • Mach, H., Dong, Z., Middaugh, C.R, Lewis, R., (1991). Conformational stability of Cu,Zn-superoxide dismutase, the apoprotein, and its zinc-substituted derivatives: second-derivative spectroscopy of phenylalanine and tyrosine residues.. Archives of biochemistry and biophysics, 287:1, 41-7.
          • Mach, H., Thomson, J.A, Middaugh, C.R, Lewis, R., (1991). Examination of phenylalanine microenvironments in proteins by second-derivative absorption spectroscopy.. Archives of biochemistry and biophysics, 287:1, 33-40.
          • Dong, Z., Lewis, R., Middaugh, C.R, (1991). Molecular mechanism of spider silk elasticity.. Archives of biochemistry and biophysics, 284:1, 53-7.
          • Kadokami, Y., Lewis, R., (1990). Membrane bound PCR.. Nucleic acids research, 18:10, 3082.
          • Hiddinga, H.J, Katzenstein, G.E, Middaugh, C.R, Lewis, R., (1990). Secondary structure characteristics of proenkephalin peptides E, B, and F.. Neurochemical research, 15:4, 393-9.
          • Mach, H., Trautman, P.A, Thomson, J.A, Lewis, R., Middaugh, C.R, (1990). Inhibition of alpha-crystallin aggregation by gamma-crystallin.. The Journal of biological chemistry, 265:9, 4844-8.
          • Lewis, R., Ray, P., Coguill, R., Kruggel, W., (1990). Presence of pancreatic trypsin inhibitor in adrenal medullary chromaffin cells.. Biochemical and biophysical research communications, 167:2, 543-7.
          • Pei, Z., Ellison, 3rd, R.T, Lewis, R., Blaser, M.J, (1988). Purification and characterization of a family of high molecular weight surface-array proteins from Campylobacter fetus.. The Journal of biological chemistry, 263:13, 6416-20.
          • Katzenstein, G.E, Lund, D., Schultz, P., Lewis, R., (1987). Target tissue distribution of the proenkephalin peptides F, E, and B.. Biochemical and biophysical research communications, 146:3, 1184-90.
          • Aird, S.D, Kaiser, I.I, Lewis, R., Kruggel, W.G, (1986). A complete amino acid sequence for the basic subunit of crotoxin.. Archives of biochemistry and biophysics, 249:2, 296-300.
          • Nishimura, R., Shin, J., Ji, I., Middaugh, C.R, Kruggel, W., Lewis, R., Ji, T.H, (1986). A single amino acid substitution in an ectopic alpha subunit of a human carcinoma choriogonadotropin.. The Journal of biological chemistry, 261:23, 10475-7.
          • Mauro, J.M, Lewis, R., Barden, R.E, (1986). Photoaffinity labelling of carnitine acetyltransferase with S-(p-azidophenacyl)thiocarnitine.. The Biochemical journal, 237:2, 533-40.
          • Hammond, D.C, Kruggel, W.G, Lewis, R., Barden, R.E, (1986). S-(4-bromo-2,3-dioxobutyl)-CoA labels two distinct sites on citrate synthase.. The Journal of biological chemistry, 261:18, 8424-8.
          • Katzenstein, G.E, Vrona, S.A, Wechsler, R.J, Steadman, B.L, Lewis, R., Middaugh, C.R, (1986). Role of conformational changes in the elution of proteins from reversed-phase HPLC columns.. Proceedings of the National Academy of Sciences of the United States of America, 83:12, 4268-72.
          • Aird, S.D, Kaiser, I.I, Lewis, R., Kruggel, W.G, (1985). Rattlesnake presynaptic neurotoxins: primary structure and evolutionary origin of the acidic subunit.. Biochemistry, 24:25, 7054-8.
          • Lewis, R., Agustin, J.S, Kruggel, W., Lardy, H.A, (1985). The structure of caltrin, the calcium-transport inhibitor of bovine seminal plasma.. Proceedings of the National Academy of Sciences of the United States of America, 82:19, 6490-1.
          • Kraemer, W.J, Noble, B., Culver, B., Lewis, R., (1985). Changes in plasma proenkephalin peptide F and catecholamine levels during graded exercise in men.. Proceedings of the National Academy of Sciences of the United States of America, 82:18, 6349-51.
          • Micanovic, R., Ray, P., Kruggel, W., Lewis, R., (1985). Purification and sequence of a novel ovine adrenal medullary peptide and its precursor.. Neuroendocrinology, 41:3, 197-200.
          • Kruggel, W.G, Lewis, R., (1985). High-performance liquid chromatographic support for the baseline separation of all phenylthiohydantoin amino acids.. Journal of chromatography, 342:2, 376-9.
          • Brandau, D.T, Ray, P., Stern, A.S, Lewis, R., (1985). New bovine adrenal medullary peptide and its precursor.. International journal of peptide and protein research, 25:3, 238-41.
          • Kruggel, W., O'Connor, D.T, Lewis, R., (1985). The amino terminal sequences of bovine and human chromogranin A and secretory protein I are identical.. Biochemical and biophysical research communications, 127:1, 380-3.
          • Kraemer, W., Noble, B., Robertson, K., Lewis, R., (1985). Response of plasma proenkephalin peptide F to exercise.. Peptides, 6 Suppl 2, 167-9.
          • Sadler, A.J, Micanovic, R., Katzenstein, G.E, Lewis, R., Middaugh, C.R, (1984). Protein conformation and reversed-phase high-performance liquid chromatography.. Journal of chromatography, 317, 93-101.
          • Micanovic, R., Kruggel, W., Ray, P., Lewis, R., (1984). Purification and sequence of a non-opioid peptide derived from ovine proenkephalin: implications for possible species specific processing.. Peptides, 5:5, 853-6.
          • Lewis, R., Micanovic, R., Ray, P., Blacher, R., Stern, A., (1984). Adrenal medullary chromaffin granule peptides: two major ovine peptides and their precursor.. Archives of biochemistry and biophysics, 230:1, 154-7.
          • Micanovic, R., Ray, P., Kruggel, W., Lewis, R., (1984). Purification and sequence of an opioid peptide derived from ovine proenkephalin.. Biochemical and biophysical research communications, 118:1, 299-303.
          • Lewis, R., Ray, P., Blacher, R., Stern, A., (1983). Isolation and sequence of a non-opioid peptide derived from proenkephalin.. Biochemical and biophysical research communications, 113:1, 229-34.
          • Lewis, R., Stern, A.S, (1983). Biosynthesis of the enkephalins and enkephalin-containing polypeptides.. Annual review of pharmacology and toxicology, 23, 353-72.
          • DeWald, D.B, Lewis, R., (1983). Enkephalin-containing polypeptide levels in normal tensive and SHR rat adrenal glands.. Peptides, 4:1, 121-3.
          • Evangelista, R., Ray, P., Lewis, R., (1982). A "trypsin-like" enzyme in adrenal chromaffin granules: a proenkephalin processing enzyme.. Biochemical and biophysical research communications, 106:3, 895-902.
          • Kilpatrick, D.L, Jones, B.N, Lewis, R., Stern, A.S, Kojima, K., Shively, J.E, Udenfriend, S., (1982). An 18,200-dalton adrenal protein that contains four [Met]enkephalin sequences.. Proceedings of the National Academy of Sciences of the United States of America, 79:9, 3057-61.
          • Jones, B.N, Shively, J.E, Kilpatrick, D.L, Stern, A.S, Lewis, R., Kojima, K., Udenfriend, S., (1982). Adrenal opioid proteins of 8600 and 12,600 daltons: intermediates in proenkephalin processing.. Proceedings of the National Academy of Sciences of the United States of America, 79:6, 2096-100.
          • Lewis, R., (1982). Enkephalin biosynthesis in the adrenal medulla.. Advances in biochemical psychopharmacology, 33, 167-74.
          • Lawson, E.Q, Schubert, C.F, Lewis, R., Middaugh, C.R, (1981). The solubility of bovine lens crystallins.. The Journal of biological chemistry, 256:13, 6523-5.
          • Fallon, A., Lewis, R., Gibson, K.D, (1981). Separation of the major species of interstitial collagen by reverse-phase high-performance liquid chromatography.. Analytical biochemistry, 110:2, 318-22.
          • Lewis, R., Stern, A.S, Kilpatrick, D.L, Gerber, L.D, Rossier, J., Stein, S., Udenfriend, S., (1981). Marked increases in large enkephalin-containing polypeptides in the rat adrenal gland following denervation.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1:1, 80-2.
          • Kilpatrick, D.L, Lewis, R., Stein, S., Udenfriend, S., (1980). Release of enkephalins and enkephalin-containing polypeptides from perfused beef adrenal glands.. Proceedings of the National Academy of Sciences of the United States of America, 77:12, 7473-5.
          • Jones, B.N, Stern, A.S, Lewis, R., Kimura, S., Stein, S., Udenfriend, S., Shively, J.E, (1980). Structure of two adrenal polypeptides containing multiple enkephalin sequences.. Archives of biochemistry and biophysics, 204:1, 392-5.
          • Inturrisi, C.E, Umans, J.G, Wolff, D., Stern, A.S, Lewis, R., Stein, S., Udenfriend, S., (1980). Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.. Proceedings of the National Academy of Sciences of the United States of America, 77:9, 5512-4.
          • Lewis, R., Stern, A.S, Kimura, S., Stein, S., Udenfriend, S., (1980). Enkephalin biosynthetic pathway: proteins of 8000 and 14,000 daltons in bovine adrenal medulla.. Proceedings of the National Academy of Sciences of the United States of America, 77:8, 5018-20.
          • Lewis, R., Stern, A.S, Kimura, S., Rossier, J., Stein, S., Udenfriend, S., (1980). An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin.. Science (New York, N.Y.), 208:4451, 1459-61.
          • Lewis, R., Fallon, A., Stein, S., Gibson, K.D, Udenfriend, S., (1980). Supports for reverse-phase high-performance liquid chromatography of large proteins.. Analytical biochemistry, 104:1, 153-9.
          • Kimura, S., Lewis, R., Stern, A.S, Rossier, J., Stein, S., Udenfriend, S., (1980). Probable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons.. Proceedings of the National Academy of Sciences of the United States of America, 77:3, 1681-5.
          • Lewis, R., Stern, A.S, Kimura, S., Rossier, J., Brink, L., Gerber, L.D, Stein, S., Udenfriend, S., (1980). Opioid peptides and precursors in the adrenal medulla.. Advances in biochemical psychopharmacology, 22, 167-79.
          • Stern, A.S, Lewis, R., Kimura, S., Rossier, J., Gerber, L.D, Brink, L., Stein, S., Udenfriend, S., (1979). Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum.. Proceedings of the National Academy of Sciences of the United States of America, 76:12, 6680-3.
          • Lewis, R., (1979). A low-cost gradient programmer.. Analytical biochemistry, 98:1, 142-5.
          • Lewis, R., Stern, A.S, Rossier, J., Stein, S., Udenfriend, S., (1979). Putative enkephalin precursors in bovine adrenal medulla.. Biochemical and biophysical research communications, 89:3, 822-9.
          • Lewis, R., Stein, S., Udenfriend, S., (1979). Separation of opioid peptides utilizing high performance liquid chromatography.. International journal of peptide and protein research, 13:5, 493-7.
          • Kimura, S., Lewis, R., Gerber, L.D, Brink, L., Rubinstein, M., Stein, S., Udenfriend, S., (1979). Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin.. Proceedings of the National Academy of Sciences of the United States of America, 76:4, 1756-9.
          • Lewis, R., Allison, W.S, (1978). The use of photoactivated hetero-bifunctional reagents to cross-link cytochrome c to proteins that bind it by electrostatic interactions.. Archives of biochemistry and biophysics, 190:1, 163-73.
          • Lewis, R., Stein, S., Gerber, L.D, Rubinstein, M., Udenfriend, S., (1978). High molecular weight opioid-containing proteins in striatum.. Proceedings of the National Academy of Sciences of the United States of America, 75:8, 4021-3.

          * Has not been peer reviewed

          Publications - Literary Journal

            * Has not been peer reviewed

            Publications - MultiMedia

              * Has not been peer reviewed

              Publications - Technical Reports

                * Has not been peer reviewed

                Publications - Translations & Transcripts

                  Publications - Other

                    Other

                  * Has not been peer reviewed

                  Scheduled Teaching

                  BIOL 5790, 6790 - Protein Structure/Function and Purification, Spring 2017

                  BIOL 4750 - Topics in Biology (Topic), Spring 2017

                  BENG 6930 - Special Problems, Fall 2016

                  BIOL 4750 - Topics in Biology (Topic), Fall 2016

                  BENG 6930 - Special Problems, Fall 2015

                  BENG 4930 - Special Studies, Fall 2015

                  BIOL 4750 - Topics in Biology (Topic), Fall 2015

                  BIOL 5790,6790 - Protein Structure/Function and Purification, Spring 2015

                  BENG 6930 - Special Problems, Spring 2015

                  BENG,BIOL 4750,4930,6750 - Special Studies, Spring 2015

                  BENG 6930 - Special Problems, Fall 2014

                  BENG 4930 - Special Studies, Fall 2014

                  BIOL 4750 - Topics in Biology (Topic), Fall 2014

                  BENG 6930 - Special Problems, Fall 2013

                  BENG 6930 - Special Problems, Spring 2013

                  BIOL 6750,7750 - Topics in Biology, Spring 2013


                  Graduate Students Mentored

                  Dan Gil, Biology, August 2014
                  Thomas Harris, Biological Engineering, August 2014
                  Kyle Berg, Biology, June 2014
                  Richard Decker, Cole Peterson, Biological Engineering, May 2012
                  Xiaoli Zhang, Biology, February 2012
                  Cameron Copeland, Michaela Hugie, Biological Engineering, May 2011
                  Justin Jones, Biology, May 2012 - May 2015
                  Chauncey Tucker, Biological Engineering, May 2012 - May 2014